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LGC Clinical Diagnostics | SeraCare is delighted to announce the expansion of our Somatic Cancer portfolio with the release of our Seraseq® gDNA HRD mutation mixes. These comprehensive reference materials support the development, validation, and clinical application of targeted NGS assays evaluating genomic instability. 

 
0710-2879
2x20 uL vials
25 ng/uL
 
 
0710-2880
2x20 uL vials
25 ng/uL
 
Seraseq® HRD gDNA
Negative RM
 

0710-2881
2x20 uL vials
25 ng/uL
 
Seraseq® HRD gDNA Features
  • Derived from tumor and matched-normal human cell lines
  • Allows blending to desired % tumor content with included SNP-matched normal cell line gDNA
  • 20 µL of both tumor and matched normal gDNA at 25 ng/µL
  • Additional biosynthetic single-nucleotide variants (SNVs) of 4 homologous recombination repair (HRR) genes
  • HRD status validated by targeted Next Generation Sequencing (NGS)
  • Manufactured in GMP-compliant, ISO 13485-certified facilities

Seraseq® FFPE HRD reference materials are also available

Seraseq® FFPE HRD Features
  • Full-process FFPE format reference material
  • Validated by NGS and microarray assays with various HRD algorithms
  •  Derived from tumor and matched-normal human cell lines
  • Blended to ~65% tumor content 
  • Additional biosynthetic SNVs of 4 HRR genes in Seraseq FFPE HRD High-Positive RM and Seraseq FFPE HRD Negative RM.
  • Manufactured in GMP-compliant, ISO 13485-certified facilities

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